AARS phylogeny

New techniques are needed for the bioinformatic analysis of the amino- acid sequences of the Amino acyl-tRNA synthetase (AARS) enzymes. Sequence alignment must be based on the three-dimensional structure of the proteins and the phylogenetic analysis must cope with the lack of amino acid discrimination in the earliest aeons. Results will elucidate the origin of genetic coding.

Assoc Prof Peter Wills
Email: p.wills@auckland.ac.nz